864 calls and 12 puts traded on Nov 4, 2026, 876 contracts in total. Open interest was 52.36K contracts. Over the past 30 days, volume averaged 1.18K contracts per day. The ANVS option volume chart shows volume by strike and expiration date.

Annovis Bio IV rank is 100, so its 30-day implied volatility of 1,000.0% is near the top of its one-year range. Over the past year it ranged from 82.6% on Jan 26, 2026 to 1,000.0% on Nov 4, 2025. See the ANVS implied volatility history for a longer view.

The Annovis Bio put/call volume ratio was 0.01 on Nov 4, 2026, so calls outnumber puts. The put/call open interest ratio was 0.03. The ANVS open interest chart shows calls and puts at each strike.

As of the Nov 4, 2026 close, max pain for Annovis Bio options about one week from expiration was $0.50, 58.3% below the $1.20 close. The ANVS max pain chart shows it for every expiration date.

Based on 7-day implied volatility of 927.7%, options price a move of about ±$1.54 (±128.5%) over the next week, a range of roughly -$0.34 to $2.74 from the Nov 4, 2026 close. The ANVS expected move chart shows it for every expiration date.