355 calls and 1.2K puts traded on Nov 4, 2026, 1.55K contracts in total. Open interest was 47.78K contracts. Over the past 30 days, volume averaged 2.08K contracts per day. The VRTX option volume chart shows volume by strike and expiration date.

Vertex Pharmaceuticals IV rank is 51, so its 30-day implied volatility of 35.8% is near the middle of its one-year range. Over the past year it ranged from 22.8% on Dec 4, 2025 to 48.3% on Feb 12, 2026. See the VRTX implied volatility history for a longer view.

The Vertex Pharmaceuticals put/call volume ratio was 3.37 on Nov 4, 2026, so puts outnumber calls. The put/call open interest ratio was 1.10. The VRTX open interest chart shows calls and puts at each strike.

As of the Nov 4, 2026 close, max pain for Vertex Pharmaceuticals options about one week from expiration was $532.14, 3.1% below the $549.12 close. The VRTX max pain chart shows it for every expiration date.

Based on 7-day implied volatility of 36.2%, options price a move of about ±$27.49 (±5.0%) over the next week, a range of roughly $521.63 to $576.61 from the Nov 4, 2026 close. The VRTX expected move chart shows it for every expiration date.